ABSTRACT
RESUMO Objetivo Identificar a ocorrência de disfunções orofaciais em pacientes infantojuvenis com leucemia aguda, submetidos à quimioterapia de remissão. Métodos Em um período de 16 meses, 40 pacientes com leucemias agudas, entre 3 e 18 anos de idade, foram admitidos em um hemocentro no estado do Amazonas. Destes, 23 foram incluídos neste estudo transversal e submetidos à avaliação das funções orofaciais, por meio do Nordic Orofacial Test-Screening (NOT-S), entre o trigésimo (D30) e o trigésimo terceiro dia (D33) da fase de indução da remissão. A presença de manifestações orais também foi avaliada por meio de exame clínico. Resultados Disfunção orofacial foi observada em, aproximadamente, metade dos casos avaliados (n=11). Destes pacientes, todos tiveram o domínio Secura de Boca (VI) alterado e 81,8% (n=9) apresentaram alteração no domínio Mastigação e Deglutição (IV). Mucosites em lábios, língua, soalho e orofaringe foram as lesões orais mais encontradas após a fase de indução. Houve associação entre a ocorrência de lesões orais nos pacientes avaliados e a presença de disfunção orofacial, segundo o NOT-S (IC 95%, p-valor = 0,027). Conclusão Sugere-se que a disfunção orofacial seja frequente na fase de indução da remissão em pacientes infantojuvenis com leucemias agudas. Estudos sobre as disfunções orofaciais nessa população, bem como sua relação com as lesões orais são necessários para melhor esclarecimento e compreensão dos impactos funcionais.
ABSTRACT Purpose To Identify the occurrence of orofacial dysfunctions in young children and adolescents with acute leukemia who are undergoing remission chemotherapy. Methods Over a period of 16 months, 40 three to eighteen year -old patients with acute leukemia were admitted to the Amazonas State Hemocenter. Of these, 23 were included in the cross-sectional study and submitted to the evaluation of orofacial functions using the Nordic Orofacial Test-Screening, between D30 and D33 of the remission induction phase. The presence of oral manifestations was also evaluated via clinical examination. Results Orofacial dysfunction was observed in approximately half of the evaluated cases (n=11). Of these patients, all had alterations in the Dryness of the Mouth (VI) domain and 81.8% (n=9) showed alterations in the Chewing and Swallowing (IV) domain. Mucosites on lips, tongue, floor of the mouth and the oropharynx were the most commonly found oral lesions after the remission induction phase. According to the NOT-S, there was an association between the occurrence of oral lesions in the evaluated patients and the presence of orofacial dysfunction (95% CI, p-value = 0.027). Conclusion It is suggested that orofacial dysfunction is frequent in the remission induction phase in children and adolescents with acute leukemia. Studies regarding these orofacial dysfunctions in this population, as well as their relationship with oral lesions, are needed in order to fully understand their functional impact.
Subject(s)
Humans , Child, Preschool , Child , Adolescent , Oral Manifestations , Stomatognathic System/drug effects , Leukemia/drug therapy , Leukemia/therapy , Drug-Related Side Effects and Adverse Reactions , BrazilABSTRACT
El bruxismo es un hábito parafuncional diurno o nocturno, caracterizado por rechinar y/o apretar los dientes. Hoy día se le concede un origen multicausal y entre los factores más relevantes figuran los psíquicos o psicosomáticos. Teniendo en cuenta las múltiples consecuencias clínicas que ocasiona, en términos de dolor, deterioro dental y osteomioarticular, se le considera uno de los trastornos orofaciales más complejos, de difícil tratamiento y pronóstico reservado. De acuerdo con la complejidad de este tema y de los conocimientos actuales al respecto, se realizó la presente investigación para describir las tendencias actuales en la fisiopatología de esta enfermedad.
Bruxismo is a day or night parafunctional habit, characterized by squeaking and/or pressing teeth. Nowadays it is considered to have a multicausal origin and among the most outstanding factors there are the psychic or psychosomatic factors. Keeping in mind the multiple clinical consequences that it causes, in terms of pain, dental and osteomyoarticular deterioration, it is considered one of the most complex orofacial dysfunctions, difficult to treat and with reserved prognosis. According to the complexity of this topic and of the current knowledge on this respect, the present investigation was carried out to describe the current tendencies in the physiopathology of this disease.